About GLM

Perna canaliculus, the Green Lipped Mussel, is produced commercially in pristine waters off the New Zealand coast. It is a nutritional whole food that possesses an exceptional degree of biological activity. This edible bivalve has been a valuable food source for the native people of New Zealand for centuries. Arthritic and rheumatic disorders are much lower among the coastal population compare to the islanders. It contains the ocean’s natural mineral balance, similar to that found in the human body.


The Green Lipped Mussel has been found to have beneficial effects in relieving the pain, inflammation and symptoms associated with:

  • Osteoarthritis (degenerative joint disease)
  • Rheumatoid Arthritis
  • Bursitis
  • Ankylosing Spondylitis
  • Sports Related Injuries
  • Lyme Disease
  • Inflammatory Skin Conditions
  • Fibromyalgia

Besides the obvious benefits for dogs and horses, preliminary studies have shown Perna to help increase sperm count and motility in breeding stock.

Anti-inflammatory Effects

One study on rats, with collagen induced arthritis, showed anti-inflammatory activity and gastroprotective properties by reducing gastric electrogenicity caused by NSAIDs (non-steroidal anti-inflammatory drugs). Another study showed an aqueous fraction of the Green Lipped Mussel also exhibited anti-inflammatory results. A study using the lipoid extract, containing inflammation in rats with polyarthritis. A study performed at Clemson University revealed that Perna was effective in preventing arthritis in addition to reversing it (in both animal and cell cultures).

Immunostimulatory Effects

The Clemson University study also showed that the mussel acted as a immunomodulating agent, affecting both humoral and cellular immunity. Dr Lawson demonstrated that an extract decreased the level of antibody production in a B-cell Hybridoma assay in a cell culture model. It also lowered the TNF-alpha (tumor necrosis factor) level in a cellular-mediated response. Perna also decreased cytokines (IL-1. IL-2 and IL-6) antibody secretion levels.